Ecdysone receptor · SINGLE PROTEIN · Lucilia cuprina
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As of 2026-09-14Protein identity stays anchored to UniProt O18531. Use UniProt O18531 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O18531 as the stable identity anchor, then attach disease evidence before program review.
Ecdysone receptor
Review this target as Ecdysone receptor, mapped to UniProt O18531. Sequence length is 757 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ecdysone receptor as ChEMBL target CHEMBL1250403, mapped to UniProt O18531. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Ecdysone receptor is the right protein anchor across sources, using UniProt O18531 as the stable mapping.
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| Preferred Name | Ecdysone receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Lucilia cuprina |
| UniProt | O18531 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ecdysone receptor |
| UniProt Accession | O18531 |
| Component Type | Protein |
| Sequence Length | 757 aa |
Ecdysone receptor
Review this target as Ecdysone receptor, mapped to UniProt O18531. Sequence length is 757 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL549789 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL1253938 | 5.26 | IC50 | 5500.0 | Preclinical |
| CHEMBL1254948 | 5.26 | IC50 | 5500.0 | Preclinical |
| CHEMBL224128 | 5.26 | IC50 | 5500.0 | Clinical |
| CHEMBL1254213 | 5.19 | IC50 | 6500.0 | Preclinical |
| CHEMBL1253279 | 5.14 | IC50 | 7250.0 | Preclinical |
| CHEMBL1254864 | 5.08 | IC50 | 8300.0 | Preclinical |
| CHEMBL1254453 | 5.07 | IC50 | 8500.0 | Preclinical |
| CHEMBL1253195 | 4.96 | IC50 | 11000.0 | Preclinical |
| CHEMBL1254214 | 4.9 | IC50 | 12500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 24 | 4.8 |