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Target Snapshot

CHEMBL1250410 Target Snapshot

Solute carrier family 2, facilitated glucose transporter member 4 · SINGLE PROTEIN · Mus musculus

7Compounds
6Assays
0Approved Drugs
3.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P14142. Use UniProt P14142 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P14142 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Solute carrier family 2, facilitated glucose transporter member 4 as ChEMBL target CHEMBL1250410, mapped to UniProt P14142. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Solute carrier family 2, facilitated glucose transporter member 4
SINGLE PROTEIN · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL1250410
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P14142
Solute carrier family 2, facilitated glucose transporter member 4
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Solute carrier family 2, facilitated glucose transporter member 4 is the right protein anchor across sources, using UniProt P14142 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSolute carrier family 2, facilitated glucose transporter member 4
UniProt AccessionP14142
Component TypeProtein
Sequence Length509 aa

Solute carrier family 2, facilitated glucose transporter member 4

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Solute carrier family 2, facilitated glucose transporter member 4, mapped to UniProt P14142. Sequence length is 509 aa.

Mapped IDP14142
Review nameSolute carrier family 2, facilitated glucose transporter member 4
OrganismMus musculus
Clinical Profile

Clinical Phase Distribution

1
Phase III
1
Phase II
Assay Mix

Activity Type Distribution

IC501.0
KI2.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL44 4.7 IC50 20000.0 Clinical
CHEMBL431701 4.22 Ki 60000.0 Clinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

6
Total Assays
3
Tested Compounds
1
Assay Types
Binding — 6 assays, 3 compounds
BAO Format Assays Compounds Avg pChEMBL
cell membrane format 2 0
cell-based format 2 3 4.5
cell-free format 1 0
subcellular format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine