Use UniProt P62834 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1255139 Target Snapshot
Ras-related protein Rap-1A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P62834. Use UniProt P62834 as the stable identity anchor, then attach disease evidence before program review.
Ras-related protein Rap-1A
Review this target as Ras-related protein Rap-1A, mapped to UniProt P62834. Sequence length is 184 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Ras-related protein Rap-1A as ChEMBL target CHEMBL1255139, mapped to UniProt P62834. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Ras-related protein Rap-1A is the right protein anchor across sources, using UniProt P62834 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Ras-related protein Rap-1A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P62834 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ras-related protein Rap-1A |
| UniProt Accession | P62834 |
| Component Type | Protein |
| Sequence Length | 184 aa |
Ras-related protein Rap-1A
How to read this target
Review this target as Ras-related protein Rap-1A, mapped to UniProt P62834. Sequence length is 184 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL159171 | 6.85 | EC50 | 140.0 | Preclinical |
| CHEMBL1269578 | 6.3 | Kd | 500.0 | Preclinical |
| CHEMBL1077126 | 5.4 | Kd | 4000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 6 assays, 3 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 3 | 2 | 5.7 |
| cell-based format | 2 | 0 | — |
| single protein format | 1 | 1 | 6.8 |