Use UniProt Q86SK9 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1275210 Target Snapshot
Stearoyl-CoA desaturase 5 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q86SK9. Use UniProt Q86SK9 as the stable identity anchor, then attach disease evidence before program review.
Stearoyl-CoA desaturase 5
Review this target as Stearoyl-CoA desaturase 5, mapped to UniProt Q86SK9. Sequence length is 330 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Stearoyl-CoA desaturase 5 as ChEMBL target CHEMBL1275210, mapped to UniProt Q86SK9. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Stearoyl-CoA desaturase 5 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q86SK9 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Stearoyl-CoA desaturase 5 |
| UniProt Accession | Q86SK9 |
| Component Type | Protein |
| Sequence Length | 330 aa |
Stearoyl-CoA desaturase 5
How to read this target
Review this target as Stearoyl-CoA desaturase 5, mapped to UniProt Q86SK9. Sequence length is 330 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5653589 | 8.89 | Kd | 1.275 | Preclinical |
| CHEMBL1950397 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL5842076 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL6023405 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL5798346 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL5902146 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL5911338 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL1950546 | 7.5 | IC50 | 32.0 | Preclinical |
| CHEMBL5839703 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL5857575 | 7.33 | IC50 | 47.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 6 assays, 240 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 240 | 5.4 |