UDP-glucuronosyltransferase 1A1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P22309. Use UniProt P22309 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P22309 as the stable identity anchor, then attach disease evidence before program review.
UDP-glucuronosyltransferase 1A1
Review this target as UDP-glucuronosyltransferase 1A1, mapped to UniProt P22309. Sequence length is 533 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats UDP-glucuronosyltransferase 1A1 as ChEMBL target CHEMBL1287617, mapped to UniProt P22309. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether UDP-glucuronosyltransferase 1A1 is the right protein anchor across sources, using UniProt P22309 as the stable mapping.
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| Preferred Name | UDP-glucuronosyltransferase 1A1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P22309 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | UDP-glucuronosyltransferase 1A1 |
| UniProt Accession | P22309 |
| Component Type | Protein |
| Sequence Length | 533 aa |
UDP-glucuronosyltransferase 1A1
Review this target as UDP-glucuronosyltransferase 1A1, mapped to UniProt P22309. Sequence length is 533 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1163 | 6.52 | IC50 | 300.0 | Approved |
| CHEMBL139702 | 6.01 | IC50 | 970.0 | Preclinical |
| CHEMBL4227228 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL5179012 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL4573938 | 5.96 | IC50 | 1100.0 | Preclinical |
| CHEMBL5437552 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL4209316 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL4794465 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL5182534 | 5.82 | IC50 | 1500.0 | Preclinical |
| CHEMBL3222137 | 5.81 | Ki | 1540.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 61 | 10 | 5.4 |
| cell-based format | 26 | 18 | 5.0 |
| assay format | 24 | 0 | — |
| microsome format | 11 | 2 | 5.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 8 | 5.5 |
| microsome format | 1 | 2 | 6.0 |