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Target Snapshot

CHEMBL1287619 Target Snapshot

Fructose-bisphosphate aldolase · SINGLE PROTEIN · Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

7Compounds
1Assays
0Approved Drugs
12.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9URB4. Use UniProt Q9URB4 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9URB4 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Fructose-bisphosphate aldolase as ChEMBL target CHEMBL1287619, mapped to UniProt Q9URB4. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Fructose-bisphosphate aldolase
SINGLE PROTEIN · Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
As of 2026-09-14
ChEMBL target ID
CHEMBL1287619
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9URB4
Fructose-bisphosphate aldolase
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Fructose-bisphosphate aldolase is the right protein anchor across sources, using UniProt Q9URB4 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelFructose-bisphosphate aldolase
UniProt AccessionQ9URB4
Component TypeProtein
Sequence Length359 aa

Fructose-bisphosphate aldolase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Fructose-bisphosphate aldolase, mapped to UniProt Q9URB4. Sequence length is 359 aa.

Mapped IDQ9URB4
Review nameFructose-bisphosphate aldolase
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Assay Mix

Activity Type Distribution

IC501.0
KI11.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1236228 8.52 Ki 3.0 Preclinical
CHEMBL1236228 8.32 IC50 4.8 Preclinical
CHEMBL1235276 6.7 Ki 200.0 Preclinical
CHEMBL1278086 6.56 Ki 276.0 Preclinical
CHEMBL1236227 6.53 Ki 297.0 Preclinical
CHEMBL1276292 6.4 Ki 400.0 Preclinical
CHEMBL1278173 6.1 Ki 800.0 Preclinical
CHEMBL1235112 4.07 Ki 85000.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
3
6.0
5
6.5
0
7.0
0
7.5
2
8.0
1
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

1
Total Assays
7
Tested Compounds
1
Assay Types
Binding — 1 assays, 7 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 1 7 6.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine