Renin · SINGLE PROTEIN · Macaca mulatta
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt Q6DLW5. Use UniProt Q6DLW5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q6DLW5 as the stable identity anchor, then attach disease evidence before program review.
Renin
Review this target as Renin, mapped to UniProt Q6DLW5. Sequence length is 406 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Renin as ChEMBL target CHEMBL1287631, mapped to UniProt Q6DLW5. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Renin is the right protein anchor across sources, using UniProt Q6DLW5 as the stable mapping.
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| Preferred Name | Renin |
| Target Type | SINGLE PROTEIN |
| Organism | Macaca mulatta |
| UniProt | Q6DLW5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Renin |
| UniProt Accession | Q6DLW5 |
| Component Type | Protein |
| Sequence Length | 406 aa |
Renin
Review this target as Renin, mapped to UniProt Q6DLW5. Sequence length is 406 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1639 | 8.92 | IC50 | 1.2 | Approved |
| CHEMBL3990145 | 8.82 | IC50 | 1.5 | Clinical |
| CHEMBL1276271 | 7.96 | IC50 | 11.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 3 | 8.6 |