Prostaglandin G/H synthase 2 · SINGLE PROTEIN · Oryctolagus cuniculus
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As of 2026-09-14Protein identity stays anchored to UniProt O02768. Use UniProt O02768 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O02768 as the stable identity anchor, then attach disease evidence before program review.
Prostaglandin G/H synthase 2
Review this target as Prostaglandin G/H synthase 2, mapped to UniProt O02768. Sequence length is 604 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prostaglandin G/H synthase 2 as ChEMBL target CHEMBL1293198, mapped to UniProt O02768. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Prostaglandin G/H synthase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
| UniProt | O02768 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prostaglandin G/H synthase 2 |
| UniProt Accession | O02768 |
| Component Type | Protein |
| Sequence Length | 604 aa |
Prostaglandin G/H synthase 2
Review this target as Prostaglandin G/H synthase 2, mapped to UniProt O02768. Sequence length is 604 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1289341 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL109745 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL1290661 | 6.75 | IC50 | 180.0 | Preclinical |
| CHEMBL1289227 | 5.62 | IC50 | 2390.0 | Preclinical |
| CHEMBL18264 | 5.55 | IC50 | 2800.0 | Preclinical |
| CHEMBL1289342 | 5.48 | IC50 | 3290.0 | Preclinical |
| CHEMBL1290662 | 5.48 | IC50 | 3310.0 | Preclinical |
| CHEMBL1289105 | 5.43 | IC50 | 3720.0 | Preclinical |
| CHEMBL1289225 | 5.42 | IC50 | 3820.0 | Preclinical |
| CHEMBL1289106 | 5.26 | IC50 | 5520.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 2 | 12 | 5.7 |