Beta-lactamase · SINGLE PROTEIN · Salmonella choleraesuis (strain SC-B67)
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As of 2026-09-14Protein identity stays anchored to UniProt Q5J463. Use UniProt Q5J463 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q5J463 as the stable identity anchor, then attach disease evidence before program review.
Beta-lactamase
Review this target as Beta-lactamase, mapped to UniProt Q5J463. Sequence length is 269 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-lactamase as ChEMBL target CHEMBL1293260, mapped to UniProt Q5J463. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Beta-lactamase is the right protein anchor across sources, using UniProt Q5J463 as the stable mapping.
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| Preferred Name | Beta-lactamase |
| Target Type | SINGLE PROTEIN |
| Organism | Salmonella choleraesuis (strain SC-B67) |
| UniProt | Q5J463 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-lactamase |
| UniProt Accession | Q5J463 |
| Component Type | Protein |
| Sequence Length | 269 aa |
Beta-lactamase
Review this target as Beta-lactamase, mapped to UniProt Q5J463. Sequence length is 269 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1605743 | 6.72 | IC50 | 190.09 | Preclinical |
| CHEMBL1331195 | 6.43 | IC50 | 372.14 | Preclinical |
| CHEMBL1724937 | 6.21 | IC50 | 619.48 | Preclinical |
| CHEMBL374632 | 6.15 | IC50 | 709.06 | Preclinical |
| CHEMBL1303641 | 6.05 | IC50 | 889.94 | Preclinical |
| CHEMBL1518886 | 5.98 | IC50 | 1043.0 | Preclinical |
| CHEMBL1583872 | 5.91 | IC50 | 1225.0 | Preclinical |
| CHEMBL1362746 | 5.87 | IC50 | 1337.0 | Preclinical |
| CHEMBL1332522 | 5.83 | IC50 | 1466.0 | Preclinical |
| CHEMBL1604962 | 5.83 | IC50 | 1489.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 51 | 5.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |