Bromodomain-containing protein 2 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P25440. Use UniProt P25440 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P25440 as the stable identity anchor, then attach disease evidence before program review.
Bromodomain-containing protein 2
Review this target as Bromodomain-containing protein 2, mapped to UniProt P25440. Sequence length is 801 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Bromodomain-containing protein 2 as ChEMBL target CHEMBL1293289, mapped to UniProt P25440. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Bromodomain-containing protein 2 is the right protein anchor across sources, using UniProt P25440 as the stable mapping.
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| Preferred Name | Bromodomain-containing protein 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P25440 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Bromodomain-containing protein 2 |
| UniProt Accession | P25440 |
| Component Type | Protein |
| Sequence Length | 801 aa |
Bromodomain-containing protein 2
Review this target as Bromodomain-containing protein 2, mapped to UniProt P25440. Sequence length is 801 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5424952 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL5432745 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL5440537 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL5440963 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL4859923 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL5401253 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL4228445 | 9.57 | Ki | 0.27 | Preclinical |
| CHEMBL4648912 | 9.57 | Kd | 0.27 | Preclinical |
| CHEMBL5422881 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL5436475 | 9.52 | IC50 | 0.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 305 | 795 | 6.9 |
| assay format | 106 | 124 | 6.6 |
| cell-based format | 66 | 18 | 6.9 |
| cell-free format | 2 | 1 | 7.0 |
| subcellular format | 2 | 1 | 8.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 12 | 2 | 6.9 |
| tissue-based format | 2 | 1 | 5.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 10 | 6.3 |
| assay format | 1 | 1 | 4.6 |