Diphosphomevalonate decarboxylase · SINGLE PROTEIN · Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
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As of 2026-09-14Protein identity stays anchored to UniProt Q9FD53. Use UniProt Q9FD53 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9FD53 as the stable identity anchor, then attach disease evidence before program review.
diphosphomevalonate decarboxylase
Review this target as Diphosphomevalonate decarboxylase, mapped to UniProt Q9FD53. ChEMBL maps the protein component as diphosphomevalonate decarboxylase. Sequence length is 317 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Diphosphomevalonate decarboxylase as ChEMBL target CHEMBL1293300, mapped to UniProt Q9FD53. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Diphosphomevalonate decarboxylase |
| Target Type | SINGLE PROTEIN |
| Organism | Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) |
| UniProt | Q9FD53 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | diphosphomevalonate decarboxylase |
| UniProt Accession | Q9FD53 |
| Component Type | Protein |
| Sequence Length | 317 aa |
diphosphomevalonate decarboxylase
Review this target as Diphosphomevalonate decarboxylase, mapped to UniProt Q9FD53. ChEMBL maps the protein component as diphosphomevalonate decarboxylase. Sequence length is 317 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1316078 | 5.38 | IC50 | 4150.0 | Preclinical |
| CHEMBL1394251 | 5.33 | IC50 | 4680.0 | Preclinical |
| CHEMBL1411202 | 5.32 | IC50 | 4740.0 | Preclinical |
| CHEMBL1435753 | 5.13 | IC50 | 7480.0 | Preclinical |
| CHEMBL1551379 | 5.12 | IC50 | 7640.0 | Preclinical |
| CHEMBL1475475 | 5.06 | IC50 | 8660.0 | Preclinical |
| CHEMBL1394263 | 5.0 | IC50 | 9980.0 | Preclinical |
| CHEMBL1512600 | 4.98 | IC50 | 10500.0 | Preclinical |
| CHEMBL1317006 | 4.94 | IC50 | 11400.0 | Preclinical |
| CHEMBL1434101 | 4.92 | IC50 | 11900.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 28 | 4.8 |