Use UniProt Q05BA5 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1293301 Target Snapshot
Nuclear receptor coactivator 3 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q05BA5. Use UniProt Q05BA5 as the stable identity anchor, then attach disease evidence before program review.
Nuclear receptor coactivator
Review this target as Nuclear receptor coactivator 3, mapped to UniProt Q05BA5. ChEMBL maps the protein component as Nuclear receptor coactivator. Sequence length is 1403 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Nuclear receptor coactivator 3 as ChEMBL target CHEMBL1293301, mapped to UniProt Q05BA5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Nuclear receptor coactivator 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q05BA5 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Nuclear receptor coactivator |
| UniProt Accession | Q05BA5 |
| Component Type | Protein |
| Sequence Length | 1403 aa |
Nuclear receptor coactivator
How to read this target
Review this target as Nuclear receptor coactivator 3, mapped to UniProt Q05BA5. ChEMBL maps the protein component as Nuclear receptor coactivator. Sequence length is 1403 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1588525 | 5.64 | IC50 | 2300.0 | Preclinical |
| CHEMBL2000517 | 5.57 | IC50 | 2690.0 | Preclinical |
| CHEMBL1384253 | 5.46 | IC50 | 3430.0 | Preclinical |
| CHEMBL2095095 | 5.42 | IC50 | 3770.0 | Preclinical |
| CHEMBL579318 | 5.37 | IC50 | 4300.0 | Preclinical |
| CHEMBL1325945 | 5.3 | IC50 | 5000.0 | Preclinical |
| CHEMBL417727 | 4.84 | IC50 | 14600.0 | Preclinical |
| CHEMBL1541973 | 4.83 | IC50 | 14800.0 | Preclinical |
| CHEMBL3189714 | 4.79 | IC50 | 16400.0 | Preclinical |
| CHEMBL1377737 | 4.78 | IC50 | 16650.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 14 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 14 | 5.0 |