Ubiquitin carboxyl-terminal hydrolase BAP1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-15Protein identity stays anchored to UniProt Q92560. Use UniProt Q92560 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q92560 as the stable identity anchor, then attach disease evidence before program review.
Ubiquitin carboxyl-terminal hydrolase BAP1
Review this target as Ubiquitin carboxyl-terminal hydrolase BAP1, mapped to UniProt Q92560. Sequence length is 729 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ubiquitin carboxyl-terminal hydrolase BAP1 as ChEMBL target CHEMBL1293314, mapped to UniProt Q92560. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Ubiquitin carboxyl-terminal hydrolase BAP1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q92560 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ubiquitin carboxyl-terminal hydrolase BAP1 |
| UniProt Accession | Q92560 |
| Component Type | Protein |
| Sequence Length | 729 aa |
Ubiquitin carboxyl-terminal hydrolase BAP1
Review this target as Ubiquitin carboxyl-terminal hydrolase BAP1, mapped to UniProt Q92560. Sequence length is 729 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1548217 | 5.05 | IC50 | 9002.3 | Preclinical |
| CHEMBL1307842 | 4.98 | IC50 | 10487.3 | Preclinical |
| CHEMBL1419387 | 4.86 | IC50 | 13926.8 | Preclinical |
| CHEMBL1609890 | 4.76 | IC50 | 17282.0 | Preclinical |
| CHEMBL1563909 | 4.74 | IC50 | 18282.8 | Preclinical |
| CHEMBL1462119 | 4.73 | IC50 | 18728.9 | Preclinical |
| CHEMBL1527746 | 4.69 | IC50 | 20376.0 | Preclinical |
| CHEMBL3189877 | 4.65 | IC50 | 22562.5 | Preclinical |
| CHEMBL1330121 | 4.64 | IC50 | 23100.9 | Preclinical |
| CHEMBL1427879 | 4.63 | IC50 | 23329.7 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 0 | — |
| assay format | 1 | 0 | — |
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 21 | 4.6 |