Neutrophil cytosol factor 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P14598. Use UniProt P14598 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P14598 as the stable identity anchor, then attach disease evidence before program review.
Neutrophil cytosol factor 1
Review this target as Neutrophil cytosol factor 1, mapped to UniProt P14598. Sequence length is 390 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Neutrophil cytosol factor 1 as ChEMBL target CHEMBL1613743, mapped to UniProt P14598. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Neutrophil cytosol factor 1 is the right protein anchor across sources, using UniProt P14598 as the stable mapping.
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| Preferred Name | Neutrophil cytosol factor 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P14598 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Neutrophil cytosol factor 1 |
| UniProt Accession | P14598 |
| Component Type | Protein |
| Sequence Length | 390 aa |
Neutrophil cytosol factor 1
Review this target as Neutrophil cytosol factor 1, mapped to UniProt P14598. Sequence length is 390 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5197024 | 7.37 | Kd | 43.0 | Preclinical |
| CHEMBL5205264 | 6.67 | Kd | 214.0 | Preclinical |
| CHEMBL5411448 | 6.66 | Ki | 220.0 | Preclinical |
| CHEMBL5410142 | 6.62 | Ki | 240.0 | Preclinical |
| CHEMBL5419067 | 6.62 | Ki | 240.0 | Preclinical |
| CHEMBL5177721 | 6.51 | Kd | 312.0 | Preclinical |
| CHEMBL5427803 | 6.51 | Ki | 310.0 | Preclinical |
| CHEMBL5410678 | 6.38 | Ki | 420.0 | Preclinical |
| CHEMBL5406295 | 6.33 | Ki | 470.0 | Preclinical |
| CHEMBL5412642 | 6.3 | Ki | 500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 32 | 49 | 3.4 |
| assay format | 16 | 68 | 5.5 |
| single protein format | 1 | 4 | 6.5 |