Use UniProt Q3S5C3 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1641337 Target Snapshot
Efflux transporter · SINGLE PROTEIN · Salmonella newport
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As of 2026-09-13Protein identity stays anchored to UniProt Q3S5C3. Use UniProt Q3S5C3 as the stable identity anchor, then attach disease evidence before program review.
Guanidinium exporter
Review this target as Efflux transporter, mapped to UniProt Q3S5C3. ChEMBL maps the protein component as Guanidinium exporter. Sequence length is 105 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Efflux transporter as ChEMBL target CHEMBL1641337, mapped to UniProt Q3S5C3. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Efflux transporter |
| Target Type | SINGLE PROTEIN |
| Organism | Salmonella newport |
| UniProt | Q3S5C3 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Guanidinium exporter |
| UniProt Accession | Q3S5C3 |
| Component Type | Protein |
| Sequence Length | 105 aa |
Guanidinium exporter
How to read this target
Review this target as Efflux transporter, mapped to UniProt Q3S5C3. ChEMBL maps the protein component as Guanidinium exporter. Sequence length is 105 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL891 | 8.4 | IC50 | 4.0 | Approved |
| CHEMBL158 | 8.22 | IC50 | 6.0 | Approved |
| CHEMBL333078 | 6.52 | IC50 | 300.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 3 assays, 3 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 3 | 7.7 |