PenB class A beta-lactamase · SINGLE PROTEIN · Burkholderia cenocepacia
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt B8R6A5. Use UniProt B8R6A5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt B8R6A5 as the stable identity anchor, then attach disease evidence before program review.
Beta-lactamase
Review this target as PenB class A beta-lactamase, mapped to UniProt B8R6A5. ChEMBL maps the protein component as Beta-lactamase. Sequence length is 312 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats PenB class A beta-lactamase as ChEMBL target CHEMBL1641339, mapped to UniProt B8R6A5. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether PenB class A beta-lactamase is the right protein anchor across sources, using UniProt B8R6A5 as the stable mapping.
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| Preferred Name | PenB class A beta-lactamase |
| Target Type | SINGLE PROTEIN |
| Organism | Burkholderia cenocepacia |
| UniProt | B8R6A5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-lactamase |
| UniProt Accession | B8R6A5 |
| Component Type | Protein |
| Sequence Length | 312 aa |
Beta-lactamase
Review this target as PenB class A beta-lactamase, mapped to UniProt B8R6A5. ChEMBL maps the protein component as Beta-lactamase. Sequence length is 312 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL404 | 6.3 | IC50 | 500.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |
| single protein format | 1 | 1 | 6.3 |