Use UniProt Q5TIX5 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1641346 Target Snapshot
Putative uncharacterized protein atpE · SINGLE PROTEIN · Mycobacterium smegmatis
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As of 2026-09-14Protein identity stays anchored to UniProt Q5TIX5. Use UniProt Q5TIX5 as the stable identity anchor, then attach disease evidence before program review.
ATP synthase subunit c
Review this target as Putative uncharacterized protein atpE, mapped to UniProt Q5TIX5. ChEMBL maps the protein component as ATP synthase subunit c. Sequence length is 86 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Putative uncharacterized protein atpE as ChEMBL target CHEMBL1641346, mapped to UniProt Q5TIX5. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Putative uncharacterized protein atpE |
| Target Type | SINGLE PROTEIN |
| Organism | Mycobacterium smegmatis |
| UniProt | Q5TIX5 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | ATP synthase subunit c |
| UniProt Accession | Q5TIX5 |
| Component Type | Protein |
| Sequence Length | 86 aa |
ATP synthase subunit c
How to read this target
Review this target as Putative uncharacterized protein atpE, mapped to UniProt Q5TIX5. ChEMBL maps the protein component as ATP synthase subunit c. Sequence length is 86 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL376488 | 8.6 | IC50 | 2.5 | Approved |
| CHEMBL1221879 | 6.12 | IC50 | 750.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 3 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 2 | 7.7 |