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Target Snapshot

CHEMBL1667669 Target Snapshot

Outer membrane protein MIP · SINGLE PROTEIN · Legionella pneumophila

47Compounds
5Assays
0Approved Drugs
74.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q70YI1. Use UniProt Q70YI1 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q70YI1 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Outer membrane protein MIP as ChEMBL target CHEMBL1667669, mapped to UniProt Q70YI1. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Outer membrane protein MIP
SINGLE PROTEIN · Legionella pneumophila
As of 2026-09-14
ChEMBL target ID
CHEMBL1667669
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q70YI1
Outer membrane protein MIP
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Outer membrane protein MIP is the right protein anchor across sources, using UniProt Q70YI1 as the stable mapping.

Jump to Protein Context
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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelOuter membrane protein MIP
UniProt AccessionQ70YI1
Component TypeProtein
Sequence Length233 aa

Outer membrane protein MIP

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Outer membrane protein MIP, mapped to UniProt Q70YI1. Sequence length is 233 aa.

Mapped IDQ70YI1
Review nameOuter membrane protein MIP
OrganismLegionella pneumophila
Assay Mix

Activity Type Distribution

IC5072.0
KI2.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4062637 6.22 Ki 598.0 Preclinical
CHEMBL4790993 5.77 IC50 1700.0 Preclinical
CHEMBL3890138 5.66 IC50 2200.0 Preclinical
CHEMBL3949202 5.62 IC50 2398.83 Preclinical
CHEMBL3930292 5.59 IC50 2570.4 Preclinical
CHEMBL3950488 5.5 IC50 3200.0 Preclinical
CHEMBL3899080 5.46 IC50 3467.37 Preclinical
CHEMBL3941933 5.41 IC50 3890.45 Preclinical
CHEMBL4794577 5.31 IC50 4900.0 Preclinical
CHEMBL3970282 5.25 IC50 5600.0 Preclinical
Distribution

pChEMBL Value Distribution

26
5.0
8
5.5
1
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

5
Total Assays
37
Tested Compounds
1
Assay Types
Binding — 5 assays, 37 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 4 32 5.0
assay format 1 5 4.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine