Use UniProt Q70YI1 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1667669 Target Snapshot
Outer membrane protein MIP · SINGLE PROTEIN · Legionella pneumophila
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As of 2026-09-14Protein identity stays anchored to UniProt Q70YI1. Use UniProt Q70YI1 as the stable identity anchor, then attach disease evidence before program review.
Outer membrane protein MIP
Review this target as Outer membrane protein MIP, mapped to UniProt Q70YI1. Sequence length is 233 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Outer membrane protein MIP as ChEMBL target CHEMBL1667669, mapped to UniProt Q70YI1. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Outer membrane protein MIP |
| Target Type | SINGLE PROTEIN |
| Organism | Legionella pneumophila |
| UniProt | Q70YI1 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Outer membrane protein MIP |
| UniProt Accession | Q70YI1 |
| Component Type | Protein |
| Sequence Length | 233 aa |
Outer membrane protein MIP
How to read this target
Review this target as Outer membrane protein MIP, mapped to UniProt Q70YI1. Sequence length is 233 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4062637 | 6.22 | Ki | 598.0 | Preclinical |
| CHEMBL4790993 | 5.77 | IC50 | 1700.0 | Preclinical |
| CHEMBL3890138 | 5.66 | IC50 | 2200.0 | Preclinical |
| CHEMBL3949202 | 5.62 | IC50 | 2398.83 | Preclinical |
| CHEMBL3930292 | 5.59 | IC50 | 2570.4 | Preclinical |
| CHEMBL3950488 | 5.5 | IC50 | 3200.0 | Preclinical |
| CHEMBL3899080 | 5.46 | IC50 | 3467.37 | Preclinical |
| CHEMBL3941933 | 5.41 | IC50 | 3890.45 | Preclinical |
| CHEMBL4794577 | 5.31 | IC50 | 4900.0 | Preclinical |
| CHEMBL3970282 | 5.25 | IC50 | 5600.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 5 assays, 37 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 32 | 5.0 |
| assay format | 1 | 5 | 4.7 |