Telomere resolvase ResT · SINGLE PROTEIN · Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680)
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-15Protein identity stays anchored to UniProt O50979. Use UniProt O50979 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O50979 as the stable identity anchor, then attach disease evidence before program review.
Telomere resolvase ResT
Review this target as Telomere resolvase ResT, mapped to UniProt O50979. Sequence length is 449 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Telomere resolvase ResT as ChEMBL target CHEMBL1667698, mapped to UniProt O50979. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Telomere resolvase ResT |
| Target Type | SINGLE PROTEIN |
| Organism | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) |
| UniProt | O50979 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Telomere resolvase ResT |
| UniProt Accession | O50979 |
| Component Type | Protein |
| Sequence Length | 449 aa |
Telomere resolvase ResT
Review this target as Telomere resolvase ResT, mapped to UniProt O50979. Sequence length is 449 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1649742 | 5.71 | IC50 | 1960.0 | Preclinical |
| CHEMBL1649743 | 5.58 | IC50 | 2620.0 | Preclinical |
| CHEMBL1451483 | 5.56 | IC50 | 2730.0 | Preclinical |
| CHEMBL1649740 | 5.5 | IC50 | 3160.0 | Preclinical |
| CHEMBL97453 | 5.06 | IC50 | 8670.0 | Preclinical |
| CHEMBL1649741 | 5.02 | IC50 | 9520.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 6 | 5.4 |