Use UniProt Q4WNT5 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1681623 Target Snapshot
Sterol 14-alpha demethylase cyp51A · SINGLE PROTEIN · Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSCA1100) (Aspergillus fumigatus)
Research home keeps recent targets
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Switch target
Move to another high-traffic target or paste a specific ChEMBL target ID.
Frame the target before identity details
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt Q4WNT5. Use UniProt Q4WNT5 as the stable identity anchor, then attach disease evidence before program review.
Sterol 14-alpha demethylase cyp51A
Review this target as Sterol 14-alpha demethylase cyp51A, mapped to UniProt Q4WNT5. Sequence length is 515 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sterol 14-alpha demethylase cyp51A as ChEMBL target CHEMBL1681623, mapped to UniProt Q4WNT5. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Start with the right source
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Sterol 14-alpha demethylase cyp51A is the right protein anchor across sources, using UniProt Q4WNT5 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardBasic Information
Verify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Sterol 14-alpha demethylase cyp51A |
| Target Type | SINGLE PROTEIN |
| Organism | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSCA1100) (Aspergillus fumigatus) |
| UniProt | Q4WNT5 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sterol 14-alpha demethylase cyp51A |
| UniProt Accession | Q4WNT5 |
| Component Type | Protein |
| Sequence Length | 515 aa |
Sterol 14-alpha demethylase cyp51A
How to read this target
Review this target as Sterol 14-alpha demethylase cyp51A, mapped to UniProt Q4WNT5. Sequence length is 515 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL64391 | 6.0 | Kd | 1010.0 | Approved |
| CHEMBL1397 | 5.57 | Kd | 2690.0 | Approved |
| CHEMBL638 | 5.44 | Kd | 3630.0 | Approved |
| CHEMBL104 | 5.32 | Kd | 4790.0 | Approved |
| CHEMBL106 | 4.92 | Kd | 11930.0 | Approved |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 1 assays, 5 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 5 | 5.5 |