Peptidyl-prolyl cis-trans isomerase D · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q08752. Use UniProt Q08752 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q08752 as the stable identity anchor, then attach disease evidence before program review.
Peptidyl-prolyl cis-trans isomerase D
Review this target as Peptidyl-prolyl cis-trans isomerase D, mapped to UniProt Q08752. Sequence length is 370 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Peptidyl-prolyl cis-trans isomerase D as ChEMBL target CHEMBL1697657, mapped to UniProt Q08752. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Peptidyl-prolyl cis-trans isomerase D |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q08752 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Peptidyl-prolyl cis-trans isomerase D |
| UniProt Accession | Q08752 |
| Component Type | Protein |
| Sequence Length | 370 aa |
Peptidyl-prolyl cis-trans isomerase D
Review this target as Peptidyl-prolyl cis-trans isomerase D, mapped to UniProt Q08752. Sequence length is 370 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL160 | 8.59 | Ki | 2.58 | Approved |
| CHEMBL160 | 8.44 | IC50 | 3.6 | Approved |
| CHEMBL4470490 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL1688203 | 7.92 | Ki | 12.0 | Preclinical |
| CHEMBL160 | 7.89 | Kd | 13.0 | Approved |
| CHEMBL1688203 | 7.0 | Kd | 101.0 | Preclinical |
| CHEMBL3799661 | 7.0 | Ki | 99.0 | Preclinical |
| CHEMBL3805631 | 6.83 | Kd | 149.0 | Preclinical |
| CHEMBL4466871 | 6.72 | IC50 | 190.0 | Preclinical |
| CHEMBL5653589 | 6.72 | Kd | 191.4 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 16 | 46 | 5.8 |
| cell-based format | 5 | 17 | 5.2 |
| assay format | 1 | 1 | 5.8 |