Cysteine protease falcipain-3 · SINGLE PROTEIN · Plasmodium falciparum
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As of 2026-09-14Protein identity stays anchored to UniProt Q9NAW4. Use UniProt Q9NAW4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9NAW4 as the stable identity anchor, then attach disease evidence before program review.
Cysteine protease falcipain-3
Review this target as Cysteine protease falcipain-3, mapped to UniProt Q9NAW4. Sequence length is 492 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cysteine protease falcipain-3 as ChEMBL target CHEMBL1697661, mapped to UniProt Q9NAW4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cysteine protease falcipain-3 |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
| UniProt | Q9NAW4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cysteine protease falcipain-3 |
| UniProt Accession | Q9NAW4 |
| Component Type | Protein |
| Sequence Length | 492 aa |
Cysteine protease falcipain-3
Review this target as Cysteine protease falcipain-3, mapped to UniProt Q9NAW4. Sequence length is 492 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3120847 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL4434685 | 7.1 | IC50 | 79.0 | Preclinical |
| CHEMBL191881 | 7.06 | IC50 | 87.0 | Preclinical |
| CHEMBL4439637 | 6.95 | IC50 | 112.0 | Preclinical |
| CHEMBL4228861 | 6.93 | IC50 | 117.0 | Preclinical |
| CHEMBL4467013 | 6.93 | IC50 | 117.0 | Preclinical |
| CHEMBL4472824 | 6.88 | IC50 | 131.0 | Preclinical |
| CHEMBL1458713 | 6.87 | IC50 | 136.0 | Preclinical |
| CHEMBL4442854 | 6.64 | IC50 | 228.0 | Preclinical |
| CHEMBL4437416 | 6.39 | IC50 | 407.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 7 | 19 | 6.3 |
| single protein format | 4 | 25 | 5.4 |