DNA dC->dU-editing enzyme APOBEC-3A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P31941. Use UniProt P31941 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P31941 as the stable identity anchor, then attach disease evidence before program review.
DNA dC->dU-editing enzyme APOBEC-3A
Review this target as DNA dC->dU-editing enzyme APOBEC-3A, mapped to UniProt P31941. Sequence length is 199 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats DNA dC->dU-editing enzyme APOBEC-3A as ChEMBL target CHEMBL1741179, mapped to UniProt P31941. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether DNA dC->dU-editing enzyme APOBEC-3A is the right protein anchor across sources, using UniProt P31941 as the stable mapping.
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| Preferred Name | DNA dC->dU-editing enzyme APOBEC-3A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P31941 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | DNA dC->dU-editing enzyme APOBEC-3A |
| UniProt Accession | P31941 |
| Component Type | Protein |
| Sequence Length | 199 aa |
DNA dC->dU-editing enzyme APOBEC-3A
Review this target as DNA dC->dU-editing enzyme APOBEC-3A, mapped to UniProt P31941. Sequence length is 199 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1586607 | 6.05 | IC50 | 892.0 | Preclinical |
| CHEMBL1362702 | 5.97 | IC50 | 1060.0 | Preclinical |
| CHEMBL1503187 | 5.97 | IC50 | 1070.0 | Preclinical |
| CHEMBL589711 | 5.97 | IC50 | 1080.0 | Preclinical |
| CHEMBL3196851 | 5.94 | IC50 | 1140.0 | Preclinical |
| CHEMBL255881 | 5.92 | IC50 | 1190.0 | Preclinical |
| CHEMBL1338153 | 5.91 | IC50 | 1240.0 | Preclinical |
| CHEMBL1704847 | 5.9 | IC50 | 1270.0 | Preclinical |
| CHEMBL1577127 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL1543727 | 5.88 | IC50 | 1310.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 466 | 5.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 4 | 4.7 |
| single protein format | 1 | 1 | 5.3 |