Mitochondrial import inner membrane translocase subunit TIM23 · SINGLE PROTEIN · Saccharomyces cerevisiae S288c
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As of 2026-09-14Protein identity stays anchored to UniProt P32897. Use UniProt P32897 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P32897 as the stable identity anchor, then attach disease evidence before program review.
Mitochondrial import inner membrane translocase subunit TIM23
Review this target as Mitochondrial import inner membrane translocase subunit TIM23, mapped to UniProt P32897. Sequence length is 222 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Mitochondrial import inner membrane translocase subunit TIM23 as ChEMBL target CHEMBL1741180, mapped to UniProt P32897. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Mitochondrial import inner membrane translocase subunit TIM23 |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
| UniProt | P32897 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mitochondrial import inner membrane translocase subunit TIM23 |
| UniProt Accession | P32897 |
| Component Type | Protein |
| Sequence Length | 222 aa |
Mitochondrial import inner membrane translocase subunit TIM23
Review this target as Mitochondrial import inner membrane translocase subunit TIM23, mapped to UniProt P32897. Sequence length is 222 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3199050 | 6.57 | IC50 | 270.0 | Preclinical |
| CHEMBL1421736 | 6.42 | IC50 | 380.0 | Preclinical |
| CHEMBL1449627 | 6.41 | IC50 | 390.0 | Preclinical |
| CHEMBL1309497 | 6.34 | IC50 | 459.0 | Preclinical |
| CHEMBL1519298 | 6.32 | IC50 | 480.0 | Preclinical |
| CHEMBL2003655 | 6.24 | IC50 | 570.0 | Preclinical |
| CHEMBL1992176 | 6.21 | IC50 | 617.0 | Preclinical |
| CHEMBL1985130 | 6.1 | IC50 | 787.0 | Preclinical |
| CHEMBL51085 | 6.06 | IC50 | 880.0 | Clinical |
| CHEMBL1323644 | 6.05 | IC50 | 897.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 705 | 5.0 |