Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase · SINGLE PROTEIN · Plasmodium berghei
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As of 2026-09-14Protein identity stays anchored to UniProt Q9BHT9. Use UniProt Q9BHT9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9BHT9 as the stable identity anchor, then attach disease evidence before program review.
glucose-6-phosphate dehydrogenase (NADP(+))
Review this target as Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, mapped to UniProt Q9BHT9. ChEMBL maps the protein component as glucose-6-phosphate dehydrogenase (NADP(+)). Sequence length is 950 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase as ChEMBL target CHEMBL1741212, mapped to UniProt Q9BHT9. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium berghei |
| UniProt | Q9BHT9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | glucose-6-phosphate dehydrogenase (NADP(+)) |
| UniProt Accession | Q9BHT9 |
| Component Type | Protein |
| Sequence Length | 950 aa |
glucose-6-phosphate dehydrogenase (NADP(+))
Review this target as Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, mapped to UniProt Q9BHT9. ChEMBL maps the protein component as glucose-6-phosphate dehydrogenase (NADP(+)). Sequence length is 950 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1335844 | 6.13 | IC50 | 741.0 | Preclinical |
| CHEMBL1729300 | 6.11 | IC50 | 781.0 | Preclinical |
| CHEMBL1413005 | 6.08 | IC50 | 840.0 | Preclinical |
| CHEMBL1353285 | 5.99 | IC50 | 1020.0 | Preclinical |
| CHEMBL3189811 | 5.99 | IC50 | 1030.0 | Preclinical |
| CHEMBL1338317 | 5.97 | IC50 | 1080.0 | Preclinical |
| CHEMBL1556351 | 5.96 | IC50 | 1110.0 | Preclinical |
| CHEMBL45152 | 5.94 | IC50 | 1150.0 | Preclinical |
| CHEMBL1342337 | 5.92 | IC50 | 1190.0 | Preclinical |
| CHEMBL1319488 | 5.91 | IC50 | 1220.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 581 | 4.8 |