Use UniProt Q9BQF6 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1741213 Target Snapshot
Sentrin-specific protease 7 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9BQF6. Use UniProt Q9BQF6 as the stable identity anchor, then attach disease evidence before program review.
Sentrin-specific protease 7
Review this target as Sentrin-specific protease 7, mapped to UniProt Q9BQF6. Sequence length is 1050 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Sentrin-specific protease 7 as ChEMBL target CHEMBL1741213, mapped to UniProt Q9BQF6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sentrin-specific protease 7 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9BQF6 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sentrin-specific protease 7 |
| UniProt Accession | Q9BQF6 |
| Component Type | Protein |
| Sequence Length | 1050 aa |
Sentrin-specific protease 7
How to read this target
Review this target as Sentrin-specific protease 7, mapped to UniProt Q9BQF6. Sequence length is 1050 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3196451 | 6.45 | IC50 | 359.0 | Preclinical |
| CHEMBL1316867 | 6.31 | IC50 | 490.0 | Preclinical |
| CHEMBL1870914 | 6.31 | IC50 | 490.0 | Preclinical |
| CHEMBL1525161 | 6.2 | IC50 | 635.0 | Preclinical |
| CHEMBL281980 | 6.16 | IC50 | 696.0 | Preclinical |
| CHEMBL1402456 | 6.12 | IC50 | 750.0 | Preclinical |
| CHEMBL1891588 | 6.12 | IC50 | 750.0 | Preclinical |
| CHEMBL3191962 | 6.12 | IC50 | 757.0 | Preclinical |
| CHEMBL1421255 | 6.1 | IC50 | 788.0 | Preclinical |
| CHEMBL1506796 | 6.1 | IC50 | 797.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Functional — 3 assays, 804 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 804 | 5.2 |
Binding — 3 assays, 11 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 10 | 5.5 |
| assay format | 1 | 1 | 5.6 |