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Target Snapshot

CHEMBL1741213 Target Snapshot

Sentrin-specific protease 7 · SINGLE PROTEIN · Homo sapiens

998Compounds
6Assays
0Approved Drugs
1,093.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9BQF6. Use UniProt Q9BQF6 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9BQF6 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Sentrin-specific protease 7 as ChEMBL target CHEMBL1741213, mapped to UniProt Q9BQF6. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Sentrin-specific protease 7
SINGLE PROTEIN · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL1741213
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9BQF6
Sentrin-specific protease 7
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Sentrin-specific protease 7 is the right protein anchor across sources, using UniProt Q9BQF6 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSentrin-specific protease 7
UniProt AccessionQ9BQF6
Component TypeProtein
Sequence Length1050 aa

Sentrin-specific protease 7

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Sentrin-specific protease 7, mapped to UniProt Q9BQF6. Sequence length is 1050 aa.

Mapped IDQ9BQF6
Review nameSentrin-specific protease 7
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Phase II
Assay Mix

Activity Type Distribution

IC501,093.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3196451 6.45 IC50 359.0 Preclinical
CHEMBL1316867 6.31 IC50 490.0 Preclinical
CHEMBL1870914 6.31 IC50 490.0 Preclinical
CHEMBL1525161 6.2 IC50 635.0 Preclinical
CHEMBL281980 6.16 IC50 696.0 Preclinical
CHEMBL1402456 6.12 IC50 750.0 Preclinical
CHEMBL1891588 6.12 IC50 750.0 Preclinical
CHEMBL3191962 6.12 IC50 757.0 Preclinical
CHEMBL1421255 6.1 IC50 788.0 Preclinical
CHEMBL1506796 6.1 IC50 797.0 Preclinical
Distribution

pChEMBL Value Distribution

470
5.0
173
5.5
27
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

6
Total Assays
804
Tested Compounds
2
Assay Types
Functional — 3 assays, 804 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 3 804 5.2
Binding — 3 assays, 11 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 2 10 5.5
assay format 1 1 5.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine