Dihydropteroate synthetase, putative · SINGLE PROTEIN · Plasmodium berghei str. ANKA
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As of 2026-09-13Protein identity stays anchored to UniProt A0A113T0T6. Use UniProt A0A113T0T6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A0A113T0T6 as the stable identity anchor, then attach disease evidence before program review.
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
Review this target as Dihydropteroate synthetase, putative, mapped to UniProt A0A113T0T6. ChEMBL maps the protein component as 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase. Sequence length is 680 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dihydropteroate synthetase, putative as ChEMBL target CHEMBL1741265, mapped to UniProt A0A113T0T6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Dihydropteroate synthetase, putative |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium berghei str. ANKA |
| UniProt | A0A113T0T6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase |
| UniProt Accession | A0A113T0T6 |
| Component Type | Protein |
| Sequence Length | 680 aa |
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
Review this target as Dihydropteroate synthetase, putative, mapped to UniProt A0A113T0T6. ChEMBL maps the protein component as 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase. Sequence length is 680 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1043 | 4.91 | IC50 | 12410.0 | Approved |
| CHEMBL48396 | 4.75 | IC50 | 17770.0 | Clinical |
| CHEMBL139596 | 4.67 | IC50 | 21510.0 | Preclinical |
| CHEMBL353260 | 4.57 | IC50 | 26700.0 | Preclinical |
| CHEMBL1246 | 4.48 | IC50 | 33260.0 | Preclinical |
| CHEMBL142844 | 4.32 | IC50 | 48000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 8 | 4.6 |