Multidrug and toxin extrusion protein 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q96FL8. Use UniProt Q96FL8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q96FL8 as the stable identity anchor, then attach disease evidence before program review.
Multidrug and toxin extrusion protein 1
Review this target as Multidrug and toxin extrusion protein 1, mapped to UniProt Q96FL8. Sequence length is 570 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Multidrug and toxin extrusion protein 1 as ChEMBL target CHEMBL1743126, mapped to UniProt Q96FL8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Multidrug and toxin extrusion protein 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q96FL8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Multidrug and toxin extrusion protein 1 |
| UniProt Accession | Q96FL8 |
| Component Type | Protein |
| Sequence Length | 570 aa |
Multidrug and toxin extrusion protein 1
Review this target as Multidrug and toxin extrusion protein 1, mapped to UniProt Q96FL8. Sequence length is 570 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL46 | 7.52 | IC50 | 30.0 | Approved |
| CHEMBL941 | 7.4 | IC50 | 40.0 | Approved |
| CHEMBL163 | 7.1 | IC50 | 80.0 | Approved |
| CHEMBL58 | 6.72 | IC50 | 190.0 | Approved |
| CHEMBL55 | 6.39 | IC50 | 410.0 | Approved |
| CHEMBL87563 | 6.3 | IC50 | 500.0 | Clinical |
| CHEMBL360861 | 6.19 | IC50 | 650.0 | Clinical |
| CHEMBL790 | 6.16 | IC50 | 700.0 | Approved |
| CHEMBL902 | 6.12 | IC50 | 760.0 | Approved |
| CHEMBL95 | 5.96 | IC50 | 1100.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 44 | 5.6 |
| single protein format | 2 | 1 | 5.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 1 | 5.0 |
| cell-based format | 1 | 7 | 5.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 2 | 5.7 |