Leukotriene C4 synthase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q16873. Use UniProt Q16873 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q16873 as the stable identity anchor, then attach disease evidence before program review.
Leukotriene C4 synthase
Review this target as Leukotriene C4 synthase, mapped to UniProt Q16873. Sequence length is 150 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Leukotriene C4 synthase as ChEMBL target CHEMBL1743183, mapped to UniProt Q16873. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Leukotriene C4 synthase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q16873 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Leukotriene C4 synthase |
| UniProt Accession | Q16873 |
| Component Type | Protein |
| Sequence Length | 150 aa |
Leukotriene C4 synthase
Review this target as Leukotriene C4 synthase, mapped to UniProt Q16873. Sequence length is 150 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3903201 | 9.61 | IC50 | 0.248 | Preclinical |
| CHEMBL3961833 | 9.55 | IC50 | 0.28 | Preclinical |
| CHEMBL4549822 | 9.55 | IC50 | 0.28 | Preclinical |
| CHEMBL4567083 | 9.44 | IC50 | 0.36 | Preclinical |
| CHEMBL4464773 | 9.42 | IC50 | 0.381 | Preclinical |
| CHEMBL3914270 | 9.32 | IC50 | 0.483 | Preclinical |
| CHEMBL5980428 | 9.32 | IC50 | 0.483 | Preclinical |
| CHEMBL4562583 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL4563433 | 9.2 | IC50 | 0.626 | Preclinical |
| CHEMBL4584584 | 9.2 | IC50 | 0.63 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 98 | 7.3 |
| assay format | 6 | 140 | 7.3 |
| cell-based format | 2 | 2 | 6.5 |
| tissue-based format | 2 | 0 | — |
| microsome format | 1 | 3 | 6.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |