Cytochrome P450 2B4 · SINGLE PROTEIN · Oryctolagus cuniculus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P00178. Use UniProt P00178 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P00178 as the stable identity anchor, then attach disease evidence before program review.
Cytochrome P450 2B4
Review this target as Cytochrome P450 2B4, mapped to UniProt P00178. Sequence length is 491 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cytochrome P450 2B4 as ChEMBL target CHEMBL1743542, mapped to UniProt P00178. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Cytochrome P450 2B4 is the right protein anchor across sources, using UniProt P00178 as the stable mapping.
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| Preferred Name | Cytochrome P450 2B4 |
| Target Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
| UniProt | P00178 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cytochrome P450 2B4 |
| UniProt Accession | P00178 |
| Component Type | Protein |
| Sequence Length | 491 aa |
Cytochrome P450 2B4
Review this target as Cytochrome P450 2B4, mapped to UniProt P00178. Sequence length is 491 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1078442 | 5.55 | Ki | 2800.0 | Preclinical |
| CHEMBL1908211 | 4.64 | Ki | 23000.0 | Preclinical |
| CHEMBL1908229 | 4.43 | Ki | 37000.0 | Preclinical |
| CHEMBL1908221 | 4.12 | Ki | 75000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 13 | 5 | 4.7 |