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Target Snapshot

CHEMBL1764934 Target Snapshot

Hemagglutinin-neuraminidase · SINGLE PROTEIN · Human parainfluenza virus 1

55Compounds
5Assays
0Approved Drugs
63.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q06992. Use UniProt Q06992 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q06992 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Hemagglutinin-neuraminidase as ChEMBL target CHEMBL1764934, mapped to UniProt Q06992. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Hemagglutinin-neuraminidase
SINGLE PROTEIN · Human parainfluenza virus 1
As of 2026-09-14
ChEMBL target ID
CHEMBL1764934
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q06992
Hemagglutinin-neuraminidase
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Hemagglutinin-neuraminidase is the right protein anchor across sources, using UniProt Q06992 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelHemagglutinin-neuraminidase
UniProt AccessionQ06992
Component TypeProtein
Sequence Length575 aa

Hemagglutinin-neuraminidase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Hemagglutinin-neuraminidase, mapped to UniProt Q06992. Sequence length is 575 aa.

Mapped IDQ06992
Review nameHemagglutinin-neuraminidase
OrganismHuman parainfluenza virus 1
Assay Mix

Activity Type Distribution

IC5063.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4794921 7.22 IC50 60.0 Preclinical
CHEMBL514002 7.0 IC50 100.0 Preclinical
CHEMBL5414785 6.46 IC50 350.0 Preclinical
CHEMBL4753314 6.37 IC50 430.0 Preclinical
CHEMBL2325808 6.34 IC50 460.0 Preclinical
CHEMBL4173228 5.84 IC50 1430.0 Preclinical
CHEMBL4745230 5.64 IC50 2300.0 Preclinical
CHEMBL5409811 5.52 IC50 3000.0 Preclinical
CHEMBL5430444 5.28 IC50 5300.0 Preclinical
CHEMBL213310 5.23 IC50 5910.0 Preclinical
Distribution

pChEMBL Value Distribution

5
5.0
4
5.5
3
6.0
2
6.5
2
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

5
Total Assays
43
Tested Compounds
1
Assay Types
Binding — 5 assays, 43 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 4 39 5.0
cell-based format 1 4 6.1

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine