Substance-P receptor · SINGLE PROTEIN · Meriones unguiculatus
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As of 2026-09-14Protein identity stays anchored to UniProt Q5DUB1. Use UniProt Q5DUB1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q5DUB1 as the stable identity anchor, then attach disease evidence before program review.
Substance-P receptor
Review this target as Substance-P receptor, mapped to UniProt Q5DUB1. Sequence length is 407 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Substance-P receptor as ChEMBL target CHEMBL1764942, mapped to UniProt Q5DUB1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Substance-P receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Meriones unguiculatus |
| UniProt | Q5DUB1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Substance-P receptor |
| UniProt Accession | Q5DUB1 |
| Component Type | Protein |
| Sequence Length | 407 aa |
Substance-P receptor
Review this target as Substance-P receptor, mapped to UniProt Q5DUB1. Sequence length is 407 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3596448 | 10.52 | IC50 | 0.03 | Preclinical |
| CHEMBL2105667 | 10.5 | Ki | 0.03162 | Clinical |
| CHEMBL3596446 | 10.3 | IC50 | 0.05 | Preclinical |
| CHEMBL3596447 | 10.3 | IC50 | 0.05 | Preclinical |
| CHEMBL1471 | 10.05 | IC50 | 0.09 | Approved |
| CHEMBL3596493 | 9.6 | IC50 | 0.25 | Preclinical |
| CHEMBL3596492 | 9.54 | IC50 | 0.29 | Preclinical |
| CHEMBL3596485 | 9.49 | IC50 | 0.32 | Preclinical |
| CHEMBL3596494 | 9.41 | IC50 | 0.39 | Preclinical |
| CHEMBL3596483 | 9.35 | IC50 | 0.45 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 10.5 |
| cell-based format | 1 | 53 | 8.2 |
| single protein format | 1 | 1 | 7.9 |