Solute carrier family 22 member 3 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt O88446. Use UniProt O88446 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O88446 as the stable identity anchor, then attach disease evidence before program review.
Solute carrier family 22 member 3
Review this target as Solute carrier family 22 member 3, mapped to UniProt O88446. Sequence length is 551 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Solute carrier family 22 member 3 as ChEMBL target CHEMBL1770033, mapped to UniProt O88446. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Solute carrier family 22 member 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | O88446 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Solute carrier family 22 member 3 |
| UniProt Accession | O88446 |
| Component Type | Protein |
| Sequence Length | 551 aa |
Solute carrier family 22 member 3
Review this target as Solute carrier family 22 member 3, mapped to UniProt O88446. Sequence length is 551 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL135 | 5.96 | IC50 | 1100.0 | Approved |
| CHEMBL110739 | 5.31 | IC50 | 4900.0 | Clinical |
| CHEMBL1498 | 5.08 | IC50 | 8400.0 | Preclinical |
| CHEMBL103 | 4.98 | IC50 | 10500.0 | Approved |
| CHEMBL405 | 4.38 | IC50 | 42000.0 | Approved |
| CHEMBL59 | 4.21 | IC50 | 62000.0 | Approved |
| CHEMBL72 | 4.17 | IC50 | 68000.0 | Approved |
| CHEMBL39 | 4.01 | IC50 | 97000.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 20 | 10 | 4.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |