Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q8TBX8. Use UniProt Q8TBX8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8TBX8 as the stable identity anchor, then attach disease evidence before program review.
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Review this target as Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, mapped to UniProt Q8TBX8. Sequence length is 421 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma as ChEMBL target CHEMBL1770034, mapped to UniProt Q8TBX8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8TBX8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma |
| UniProt Accession | Q8TBX8 |
| Component Type | Protein |
| Sequence Length | 421 aa |
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Review this target as Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, mapped to UniProt Q8TBX8. Sequence length is 421 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4454033 | 10.64 | Kd | 0.023 | Preclinical |
| CHEMBL4436648 | 8.8 | Kd | 1.6 | Preclinical |
| CHEMBL3688339 | 8.52 | Kd | 3.0 | Preclinical |
| CHEMBL4455633 | 8.47 | Kd | 3.4 | Preclinical |
| CHEMBL4446338 | 8.32 | Kd | 4.8 | Preclinical |
| CHEMBL5653589 | 8.28 | Kd | 5.258 | Preclinical |
| CHEMBL5440409 | 8.15 | Kd | 7.1 | Preclinical |
| CHEMBL5394000 | 8.1 | IC50 | 7.943 | Preclinical |
| CHEMBL5420914 | 8.1 | IC50 | 7.943 | Preclinical |
| CHEMBL5399468 | 7.9 | IC50 | 12.59 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 74 | 119 | 5.9 |
| cell-based format | 46 | 15 | 6.5 |
| subcellular format | 32 | 25 | 5.9 |
| assay format | 25 | 44 | 6.9 |