6-phosphogluconate dehydrogenase, decarboxylating, putative · SINGLE PROTEIN · Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
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As of 2026-09-14Protein identity stays anchored to UniProt Q38DI7. Use UniProt Q38DI7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q38DI7 as the stable identity anchor, then attach disease evidence before program review.
6-phosphogluconate dehydrogenase, decarboxylating
Review this target as 6-phosphogluconate dehydrogenase, decarboxylating, putative, mapped to UniProt Q38DI7. ChEMBL maps the protein component as 6-phosphogluconate dehydrogenase, decarboxylating. Sequence length is 479 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 6-phosphogluconate dehydrogenase, decarboxylating, putative as ChEMBL target CHEMBL1770043, mapped to UniProt Q38DI7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 6-phosphogluconate dehydrogenase, decarboxylating, putative |
| Target Type | SINGLE PROTEIN |
| Organism | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) |
| UniProt | Q38DI7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 6-phosphogluconate dehydrogenase, decarboxylating |
| UniProt Accession | Q38DI7 |
| Component Type | Protein |
| Sequence Length | 479 aa |
6-phosphogluconate dehydrogenase, decarboxylating
Review this target as 6-phosphogluconate dehydrogenase, decarboxylating, putative, mapped to UniProt Q38DI7. ChEMBL maps the protein component as 6-phosphogluconate dehydrogenase, decarboxylating. Sequence length is 479 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL116018 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL324609 | 7.46 | Ki | 35.0 | Preclinical |
| CHEMBL114269 | 7.1 | Ki | 80.0 | Preclinical |
| CHEMBL323922 | 5.82 | Ki | 1520.0 | Preclinical |
| CHEMBL1235136 | 5.24 | IC50 | 5800.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 5 | 6.7 |