Use UniProt P9WKD7 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1770044 Target Snapshot
Ribose-5-phosphate isomerase B · SINGLE PROTEIN · Mycobacterium tuberculosis
Research home keeps recent targets
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Switch target
Move to another high-traffic target or paste a specific ChEMBL target ID.
Frame the target before identity details
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P9WKD7. Use UniProt P9WKD7 as the stable identity anchor, then attach disease evidence before program review.
Ribose-5-phosphate isomerase B
Review this target as Ribose-5-phosphate isomerase B, mapped to UniProt P9WKD7. Sequence length is 162 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ribose-5-phosphate isomerase B as ChEMBL target CHEMBL1770044, mapped to UniProt P9WKD7. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Start with the right source
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Ribose-5-phosphate isomerase B is the right protein anchor across sources, using UniProt P9WKD7 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardBasic Information
Verify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Ribose-5-phosphate isomerase B |
| Target Type | SINGLE PROTEIN |
| Organism | Mycobacterium tuberculosis |
| UniProt | P9WKD7 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ribose-5-phosphate isomerase B |
| UniProt Accession | P9WKD7 |
| Component Type | Protein |
| Sequence Length | 162 aa |
Ribose-5-phosphate isomerase B
How to read this target
Review this target as Ribose-5-phosphate isomerase B, mapped to UniProt P9WKD7. Sequence length is 162 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1173785 | 5.05 | Ki | 9000.0 | Preclinical |
| CHEMBL1173785 | 4.68 | IC50 | 21000.0 | Preclinical |
| CHEMBL5592442 | 4.4 | Ki | 40000.0 | Preclinical |
| CHEMBL116018 | 4.24 | Ki | 57000.0 | Preclinical |
| CHEMBL5590183 | 4.1 | Ki | 80000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 10 assays, 7 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 7 | 4.5 |