Glycogen synthase kinase 3 · SINGLE PROTEIN · Plasmodium falciparum (isolate 3D7)
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As of 2026-09-14Protein identity stays anchored to UniProt O77344. Use UniProt O77344 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O77344 as the stable identity anchor, then attach disease evidence before program review.
Glycogen synthase kinase 3
Review this target as Glycogen synthase kinase 3, mapped to UniProt O77344. Sequence length is 440 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glycogen synthase kinase 3 as ChEMBL target CHEMBL1781857, mapped to UniProt O77344. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glycogen synthase kinase 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum (isolate 3D7) |
| UniProt | O77344 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glycogen synthase kinase 3 |
| UniProt Accession | O77344 |
| Component Type | Protein |
| Sequence Length | 440 aa |
Glycogen synthase kinase 3
Review this target as Glycogen synthase kinase 3, mapped to UniProt O77344. Sequence length is 440 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5208060 | 9.31 | IC50 | 0.49 | Preclinical |
| CHEMBL361708 | 7.64 | IC50 | 23.0 | Preclinical |
| CHEMBL5176863 | 7.1 | IC50 | 79.0 | Preclinical |
| CHEMBL5186081 | 7.01 | IC50 | 97.0 | Preclinical |
| CHEMBL5207951 | 6.91 | IC50 | 124.0 | Preclinical |
| CHEMBL5180806 | 6.78 | IC50 | 165.0 | Preclinical |
| CHEMBL5173813 | 6.76 | IC50 | 172.0 | Preclinical |
| CHEMBL5197512 | 6.76 | IC50 | 174.0 | Preclinical |
| CHEMBL5198648 | 6.65 | IC50 | 223.0 | Preclinical |
| CHEMBL5202515 | 6.65 | IC50 | 226.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 27 | 6.7 |