Use UniProt P46720 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1781859 Target Snapshot
Solute carrier organic anion transporter family member 1A1 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P46720. Use UniProt P46720 as the stable identity anchor, then attach disease evidence before program review.
Solute carrier organic anion transporter family member 1A1
Review this target as Solute carrier organic anion transporter family member 1A1, mapped to UniProt P46720. Sequence length is 670 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Solute carrier organic anion transporter family member 1A1 as ChEMBL target CHEMBL1781859, mapped to UniProt P46720. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Solute carrier organic anion transporter family member 1A1 is the right protein anchor across sources, using UniProt P46720 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Solute carrier organic anion transporter family member 1A1 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P46720 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Solute carrier organic anion transporter family member 1A1 |
| UniProt Accession | P46720 |
| Component Type | Protein |
| Sequence Length | 670 aa |
Solute carrier organic anion transporter family member 1A1
How to read this target
Review this target as Solute carrier organic anion transporter family member 1A1, mapped to UniProt P46720. Sequence length is 670 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1628111 | 5.96 | Ki | 1100.0 | Preclinical |
| CHEMBL1614647 | 5.89 | Ki | 1300.0 | Preclinical |
| CHEMBL494753 | 5.89 | Ki | 1300.0 | Approved |
| CHEMBL2075012 | 5.8 | Ki | 1600.0 | Preclinical |
| CHEMBL453904 | 5.7 | Ki | 1980.0 | Preclinical |
| CHEMBL2074598 | 5.62 | Ki | 2400.0 | Preclinical |
| CHEMBL2074651 | 5.42 | Ki | 3800.0 | Preclinical |
| CHEMBL135 | 5.33 | Ki | 4700.0 | Approved |
| CHEMBL110739 | 5.28 | Ki | 5300.0 | Clinical |
| CHEMBL386630 | 5.27 | Ki | 5400.0 | Approved |
pChEMBL Value Distribution
Assay Landscape
Functional — 175 assays, 22 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 168 | 22 | 5.1 |
| organism-based format | 4 | 0 | — |
| assay format | 2 | 0 | — |
| subcellular format | 1 | 0 | — |
ADME — 3 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 0 | — |