Use UniProt O35913 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1781860 Target Snapshot
Solute carrier organic anion transporter family member 1A4 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt O35913. Use UniProt O35913 as the stable identity anchor, then attach disease evidence before program review.
Solute carrier organic anion transporter family member 1A4
Review this target as Solute carrier organic anion transporter family member 1A4, mapped to UniProt O35913. Sequence length is 661 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Solute carrier organic anion transporter family member 1A4 as ChEMBL target CHEMBL1781860, mapped to UniProt O35913. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Solute carrier organic anion transporter family member 1A4 is the right protein anchor across sources, using UniProt O35913 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Solute carrier organic anion transporter family member 1A4 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | O35913 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Solute carrier organic anion transporter family member 1A4 |
| UniProt Accession | O35913 |
| Component Type | Protein |
| Sequence Length | 661 aa |
Solute carrier organic anion transporter family member 1A4
How to read this target
Review this target as Solute carrier organic anion transporter family member 1A4, mapped to UniProt O35913. Sequence length is 661 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1751 | 7.43 | Ki | 37.0 | Approved |
| CHEMBL374478 | 5.85 | Ki | 1400.0 | Approved |
| CHEMBL633 | 5.75 | Ki | 1800.0 | Approved |
| CHEMBL170 | 5.42 | Ki | 3810.0 | Approved |
| CHEMBL437765 | 5.14 | Ki | 7300.0 | Approved |
| CHEMBL2074656 | 4.43 | Ki | 37000.0 | Preclinical |
| CHEMBL224867 | 4.41 | Ki | 39400.0 | Preclinical |
| CHEMBL1544 | 4.3 | IC50 | 50400.0 | Approved |
| CHEMBL897 | 4.14 | Ki | 72900.0 | Approved |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Functional — 58 assays, 11 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 52 | 11 | 5.4 |
| organism-based format | 5 | 0 | — |
| assay format | 1 | 0 | — |
ADME — 3 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 0 | — |