Use UniProt Q9BJF5 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1781862 Target Snapshot
Calmodulin-domain protein kinase 1 · SINGLE PROTEIN · Toxoplasma gondii
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As of 2026-09-14Protein identity stays anchored to UniProt Q9BJF5. Use UniProt Q9BJF5 as the stable identity anchor, then attach disease evidence before program review.
non-specific serine/threonine protein kinase
Review this target as Calmodulin-domain protein kinase 1, mapped to UniProt Q9BJF5. ChEMBL maps the protein component as non-specific serine/threonine protein kinase. Sequence length is 507 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Calmodulin-domain protein kinase 1 as ChEMBL target CHEMBL1781862, mapped to UniProt Q9BJF5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Calmodulin-domain protein kinase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Toxoplasma gondii |
| UniProt | Q9BJF5 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | non-specific serine/threonine protein kinase |
| UniProt Accession | Q9BJF5 |
| Component Type | Protein |
| Sequence Length | 507 aa |
non-specific serine/threonine protein kinase
How to read this target
Review this target as Calmodulin-domain protein kinase 1, mapped to UniProt Q9BJF5. ChEMBL maps the protein component as non-specific serine/threonine protein kinase. Sequence length is 507 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2079167 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL2079170 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL2079317 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL5853465 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL5926676 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL2078865 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL4591429 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL2079232 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL4553699 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL4571877 | 9.0 | IC50 | 1.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 14 assays, 508 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 12 | 432 | 7.7 |
| assay format | 1 | 28 | 7.5 |
| cell-free format | 1 | 48 | 7.1 |