Beta-arrestin-1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P49407. Use UniProt P49407 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P49407 as the stable identity anchor, then attach disease evidence before program review.
Beta-arrestin-1
Review this target as Beta-arrestin-1, mapped to UniProt P49407. Sequence length is 418 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-arrestin-1 as ChEMBL target CHEMBL1795088, mapped to UniProt P49407. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Beta-arrestin-1 is the right protein anchor across sources, using UniProt P49407 as the stable mapping.
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| Preferred Name | Beta-arrestin-1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P49407 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-arrestin-1 |
| UniProt Accession | P49407 |
| Component Type | Protein |
| Sequence Length | 418 aa |
Beta-arrestin-1
Review this target as Beta-arrestin-1, mapped to UniProt P49407. Sequence length is 418 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5417669 | 9.31 | EC50 | 0.4898 | Preclinical |
| CHEMBL5414487 | 8.03 | EC50 | 9.333 | Preclinical |
| CHEMBL593662 | 7.69 | EC50 | 20.42 | Preclinical |
| CHEMBL5653589 | 7.34 | Kd | 45.21 | Preclinical |
| CHEMBL5739600 | 7.22 | EC50 | 60.0 | Preclinical |
| CHEMBL5421473 | 7.02 | EC50 | 95.5 | Preclinical |
| CHEMBL5401911 | 6.93 | EC50 | 117.49 | Preclinical |
| CHEMBL5421352 | 6.76 | EC50 | 173.78 | Preclinical |
| CHEMBL5905642 | 6.57 | EC50 | 270.0 | Preclinical |
| CHEMBL5665374 | 6.51 | EC50 | 310.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 11 | 6.9 |
| assay format | 1 | 9 | 5.9 |
| single protein format | 1 | 1 | 7.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |