Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9GZU7. Use UniProt Q9GZU7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9GZU7 as the stable identity anchor, then attach disease evidence before program review.
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Review this target as Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, mapped to UniProt Q9GZU7. Sequence length is 261 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 as ChEMBL target CHEMBL1795098, mapped to UniProt Q9GZU7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9GZU7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
| UniProt Accession | Q9GZU7 |
| Component Type | Protein |
| Sequence Length | 261 aa |
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Review this target as Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, mapped to UniProt Q9GZU7. Sequence length is 261 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1464280 | 6.39 | IC50 | 408.0 | Preclinical |
| CHEMBL1533230 | 6.34 | IC50 | 453.0 | Preclinical |
| CHEMBL1360585 | 6.27 | IC50 | 540.0 | Preclinical |
| CHEMBL1477703 | 6.2 | IC50 | 632.0 | Preclinical |
| CHEMBL1309432 | 6.15 | IC50 | 711.0 | Preclinical |
| CHEMBL3212539 | 6.13 | IC50 | 737.0 | Preclinical |
| CHEMBL1325664 | 6.08 | IC50 | 836.0 | Preclinical |
| CHEMBL1967028 | 6.07 | IC50 | 844.0 | Preclinical |
| CHEMBL1517799 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL1361920 | 5.99 | IC50 | 1025.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 4 | 5.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 999 | 5.2 |