N-lysine methyltransferase KMT5A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9NQR1. Use UniProt Q9NQR1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9NQR1 as the stable identity anchor, then attach disease evidence before program review.
N-lysine methyltransferase KMT5A
Review this target as N-lysine methyltransferase KMT5A, mapped to UniProt Q9NQR1. Sequence length is 393 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats N-lysine methyltransferase KMT5A as ChEMBL target CHEMBL1795176, mapped to UniProt Q9NQR1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | N-lysine methyltransferase KMT5A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9NQR1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | N-lysine methyltransferase KMT5A |
| UniProt Accession | Q9NQR1 |
| Component Type | Protein |
| Sequence Length | 393 aa |
N-lysine methyltransferase KMT5A
Review this target as N-lysine methyltransferase KMT5A, mapped to UniProt Q9NQR1. Sequence length is 393 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3934996 | 7.3 | Ki | 50.0 | Preclinical |
| CHEMBL337173 | 6.68 | IC50 | 210.0 | Preclinical |
| CHEMBL3934996 | 6.48 | IC50 | 330.0 | Preclinical |
| CHEMBL290904 | 6.43 | IC50 | 370.0 | Preclinical |
| CHEMBL3414625 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL580421 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL4791952 | 6.09 | IC50 | 804.0 | Preclinical |
| CHEMBL4793474 | 5.89 | Kd | 1300.0 | Preclinical |
| CHEMBL4793474 | 5.72 | IC50 | 1900.0 | Preclinical |
| CHEMBL3318284 | 5.7 | Ki | 2000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 73 | 7 | 5.9 |
| assay format | 21 | 39 | 4.7 |
| cell-based format | 5 | 5 | 5.9 |