Proton-coupled folate transporter · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q96NT5. Use UniProt Q96NT5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q96NT5 as the stable identity anchor, then attach disease evidence before program review.
Proton-coupled folate transporter
Review this target as Proton-coupled folate transporter, mapped to UniProt Q96NT5. Sequence length is 459 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Proton-coupled folate transporter as ChEMBL target CHEMBL1795188, mapped to UniProt Q96NT5. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Proton-coupled folate transporter is the right protein anchor across sources, using UniProt Q96NT5 as the stable mapping.
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| Preferred Name | Proton-coupled folate transporter |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q96NT5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Proton-coupled folate transporter |
| UniProt Accession | Q96NT5 |
| Component Type | Protein |
| Sequence Length | 459 aa |
Proton-coupled folate transporter
Review this target as Proton-coupled folate transporter, mapped to UniProt Q96NT5. Sequence length is 459 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4445651 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL1834488 | 8.48 | IC50 | 3.3 | Preclinical |
| CHEMBL4538151 | 8.42 | IC50 | 3.82 | Preclinical |
| CHEMBL4540298 | 8.34 | IC50 | 4.57 | Preclinical |
| CHEMBL4465095 | 8.3 | IC50 | 5.01 | Preclinical |
| CHEMBL365307 | 8.28 | IC50 | 5.21 | Preclinical |
| CHEMBL3628344 | 8.27 | IC50 | 5.39 | Preclinical |
| CHEMBL3628346 | 8.19 | IC50 | 6.51 | Preclinical |
| CHEMBL225072 | 8.08 | IC50 | 8.3 | Approved |
| CHEMBL4214638 | 8.05 | IC50 | 8.98 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 43 | 37 | 7.0 |
| assay format | 1 | 0 | — |
| single protein format | 1 | 0 | — |