Use UniProt Q14004 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1795192 Target Snapshot
Cyclin-dependent kinase 13 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q14004. Use UniProt Q14004 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-dependent kinase 13
Review this target as Cyclin-dependent kinase 13, mapped to UniProt Q14004. Sequence length is 1512 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Cyclin-dependent kinase 13 as ChEMBL target CHEMBL1795192, mapped to UniProt Q14004. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Cyclin-dependent kinase 13 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q14004 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-dependent kinase 13 |
| UniProt Accession | Q14004 |
| Component Type | Protein |
| Sequence Length | 1512 aa |
Cyclin-dependent kinase 13
How to read this target
Review this target as Cyclin-dependent kinase 13, mapped to UniProt Q14004. Sequence length is 1512 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4797074 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL574738 | 9.03 | Kd | 0.94 | Preclinical |
| CHEMBL4855324 | 8.7 | Kd | 2.0 | Preclinical |
| CHEMBL4778361 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL4781207 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL4784925 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL445813 | 8.49 | Kd | 3.2 | Clinical |
| CHEMBL4760738 | 8.42 | IC50 | 3.8 | Preclinical |
| CHEMBL4744778 | 8.41 | IC50 | 3.9 | Preclinical |
| CHEMBL4791883 | 8.4 | IC50 | 4.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 127 assays, 104 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 74 | 90 | 7.4 |
| cell-based format | 20 | 2 | 7.2 |
| subcellular format | 17 | 11 | 5.9 |
| assay format | 16 | 1 | 8.3 |
Functional — 6 assays, 1 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 1 | 7.5 |