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Target Snapshot

CHEMBL1795192 Target Snapshot

Cyclin-dependent kinase 13 · SINGLE PROTEIN · Homo sapiens

518Compounds
133Assays
0Approved Drugs
477.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt Q14004. Use UniProt Q14004 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q14004 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Cyclin-dependent kinase 13 as ChEMBL target CHEMBL1795192, mapped to UniProt Q14004. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Cyclin-dependent kinase 13
SINGLE PROTEIN · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL1795192
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
Q14004
Cyclin-dependent kinase 13
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Cyclin-dependent kinase 13 is the right protein anchor across sources, using UniProt Q14004 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCyclin-dependent kinase 13
UniProt AccessionQ14004
Component TypeProtein
Sequence Length1512 aa

Cyclin-dependent kinase 13

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Cyclin-dependent kinase 13, mapped to UniProt Q14004. Sequence length is 1512 aa.

Mapped IDQ14004
Review nameCyclin-dependent kinase 13
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

6
Phase III
7
Phase II
6
Phase I
Assay Mix

Activity Type Distribution

IC50144.0
EC505.0
KD328.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4797074 9.05 IC50 0.9 Preclinical
CHEMBL574738 9.03 Kd 0.94 Preclinical
CHEMBL4855324 8.7 Kd 2.0 Preclinical
CHEMBL4778361 8.52 IC50 3.0 Preclinical
CHEMBL4781207 8.52 IC50 3.0 Preclinical
CHEMBL4784925 8.52 IC50 3.0 Preclinical
CHEMBL445813 8.49 Kd 3.2 Clinical
CHEMBL4760738 8.42 IC50 3.8 Preclinical
CHEMBL4744778 8.41 IC50 3.9 Preclinical
CHEMBL4791883 8.4 IC50 4.0 Preclinical
Distribution

pChEMBL Value Distribution

8
5.0
7
5.5
18
6.0
16
6.5
38
7.0
34
7.5
47
8.0
7
8.5
3
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

133
Total Assays
104
Tested Compounds
2
Assay Types
Binding — 127 assays, 104 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 74 90 7.4
cell-based format 20 2 7.2
subcellular format 17 11 5.9
assay format 16 1 8.3
Functional — 6 assays, 1 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 6 1 7.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine