STE20-related kinase adapter protein alpha · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q7RTN6. Use UniProt Q7RTN6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q7RTN6 as the stable identity anchor, then attach disease evidence before program review.
STE20-related kinase adapter protein alpha
Review this target as STE20-related kinase adapter protein alpha, mapped to UniProt Q7RTN6. Sequence length is 431 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats STE20-related kinase adapter protein alpha as ChEMBL target CHEMBL1795198, mapped to UniProt Q7RTN6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | STE20-related kinase adapter protein alpha |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q7RTN6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | STE20-related kinase adapter protein alpha |
| UniProt Accession | Q7RTN6 |
| Component Type | Protein |
| Sequence Length | 431 aa |
STE20-related kinase adapter protein alpha
Review this target as STE20-related kinase adapter protein alpha, mapped to UniProt Q7RTN6. Sequence length is 431 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3752910 | 7.7 | Kd | 19.76 | Preclinical |
| CHEMBL1231124 | 6.5 | Kd | 316.0 | Clinical |
| CHEMBL1088751 | 6.17 | Kd | 672.0 | Clinical |
| CHEMBL4088216 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL4097778 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL4549667 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL377300 | 5.94 | Kd | 1137.0 | Clinical |
| CHEMBL296468 | 5.55 | Kd | 2807.0 | Preclinical |
| CHEMBL1789941 | 5.43 | Kd | 3672.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| subcellular format | 18 | 5 | 5.9 |
| cell-based format | 14 | 0 | — |
| single protein format | 9 | 4 | 6.4 |