Sodium/potassium-transporting ATPase subunit alpha-1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P05023. Use UniProt P05023 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P05023 as the stable identity anchor, then attach disease evidence before program review.
Sodium/potassium-transporting ATPase subunit alpha-1
Review this target as Sodium/potassium-transporting ATPase subunit alpha-1, mapped to UniProt P05023. Sequence length is 1023 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sodium/potassium-transporting ATPase subunit alpha-1 as ChEMBL target CHEMBL1807, mapped to UniProt P05023. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sodium/potassium-transporting ATPase subunit alpha-1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P05023 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sodium/potassium-transporting ATPase subunit alpha-1 |
| UniProt Accession | P05023 |
| Component Type | Protein |
| Sequence Length | 1023 aa |
Sodium/potassium-transporting ATPase subunit alpha-1
Review this target as Sodium/potassium-transporting ATPase subunit alpha-1, mapped to UniProt P05023. Sequence length is 1023 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3752910 | 8.17 | Kd | 6.82 | Preclinical |
| CHEMBL1751 | 6.54 | IC50 | 290.0 | Approved |
| CHEMBL3594278 | 6.47 | IC50 | 340.0 | Preclinical |
| CHEMBL5653589 | 6.26 | Kd | 552.65 | Preclinical |
| CHEMBL3594276 | 6.24 | IC50 | 570.0 | Preclinical |
| CHEMBL3856118 | 5.01 | IC50 | 9800.0 | Preclinical |
| CHEMBL3594280 | 4.96 | IC50 | 11000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 7 | 6.2 |