Peptidoglycan D,D-transpeptidase MrdA · SINGLE PROTEIN · Escherichia coli K-12
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As of 2026-09-13Protein identity stays anchored to UniProt P0AD65. Use UniProt P0AD65 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P0AD65 as the stable identity anchor, then attach disease evidence before program review.
Peptidoglycan D,D-transpeptidase MrdA
Review this target as Peptidoglycan D,D-transpeptidase MrdA, mapped to UniProt P0AD65. Sequence length is 633 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Peptidoglycan D,D-transpeptidase MrdA as ChEMBL target CHEMBL1840, mapped to UniProt P0AD65. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Peptidoglycan D,D-transpeptidase MrdA |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli K-12 |
| UniProt | P0AD65 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Peptidoglycan D,D-transpeptidase MrdA |
| UniProt Accession | P0AD65 |
| Component Type | Protein |
| Sequence Length | 633 aa |
Peptidoglycan D,D-transpeptidase MrdA
Review this target as Peptidoglycan D,D-transpeptidase MrdA, mapped to UniProt P0AD65. Sequence length is 633 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4560540 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL4470489 | 7.77 | IC50 | 17.0 | Preclinical |
| CHEMBL4476279 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL4515223 | 6.24 | IC50 | 570.0 | Preclinical |
| CHEMBL2107817 | 6.23 | IC50 | 590.0 | Approved |
| CHEMBL333330 | 4.85 | IC50 | 14000.0 | Preclinical |
| CHEMBL6461 | 4.47 | IC50 | 34000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 5 | 4.7 |
| assay format | 2 | 5 | 7.2 |