Potassium voltage-gated channel subfamily KQT member 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P51787. Use UniProt P51787 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P51787 as the stable identity anchor, then attach disease evidence before program review.
Potassium voltage-gated channel subfamily KQT member 1
Review this target as Potassium voltage-gated channel subfamily KQT member 1, mapped to UniProt P51787. Sequence length is 676 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Potassium voltage-gated channel subfamily KQT member 1 as ChEMBL target CHEMBL1866, mapped to UniProt P51787. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Potassium voltage-gated channel subfamily KQT member 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P51787 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Potassium voltage-gated channel subfamily KQT member 1 |
| UniProt Accession | P51787 |
| Component Type | Protein |
| Sequence Length | 676 aa |
Potassium voltage-gated channel subfamily KQT member 1
Review this target as Potassium voltage-gated channel subfamily KQT member 1, mapped to UniProt P51787. Sequence length is 676 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2070953 | 6.58 | EC50 | 260.0 | Preclinical |
| CHEMBL2070970 | 6.38 | EC50 | 420.0 | Preclinical |
| CHEMBL2070988 | 6.22 | EC50 | 600.0 | Preclinical |
| CHEMBL2070954 | 6.16 | EC50 | 700.0 | Preclinical |
| CHEMBL2070968 | 6.14 | EC50 | 730.0 | Preclinical |
| CHEMBL2070962 | 6.11 | EC50 | 780.0 | Preclinical |
| CHEMBL2070961 | 6.09 | EC50 | 810.0 | Preclinical |
| CHEMBL2070964 | 6.06 | EC50 | 880.0 | Preclinical |
| CHEMBL2070952 | 6.05 | EC50 | 890.0 | Preclinical |
| CHEMBL2070958 | 6.0 | EC50 | 1000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 18 | 4 | 5.4 |
| cell-based format | 13 | 30 | 5.8 |
| assay format | 2 | 1 | 4.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 1 | 4.3 |
| single protein format | 4 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 1 | 5.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 4.5 |