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Target Snapshot

CHEMBL1877 Target Snapshot

Probable arabinosyltransferase A · SINGLE PROTEIN · Mycobacterium tuberculosis

3Compounds
2Assays
0Approved Drugs
3.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Probable arabinosyltransferase A shows approved-linked disease relevance led by pulmonary tuberculosis. 3 more disease programs remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt P9WNL9. Start with pulmonary tuberculosis, then reuse UniProt P9WNL9 as the stable protein anchor across project notes and exports.

Review focus
Review-ready target frame

Start with pulmonary tuberculosis, then reuse UniProt P9WNL9 as the stable protein anchor across project notes and exports.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14 1 linked drug
Open source guide
Disease program
pulmonary tuberculosis

Probable arabinosyltransferase A shows approved-linked disease relevance led by pulmonary tuberculosis. 3 more disease programs remain visible in the same review block. 1 linked drug remains visible in the same block.

Start review with pulmonary tuberculosis because it currently carries approved-linked support. Linked drugs include ETHAMBUTOL HYDROCHLORIDE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Disease source · ChEMBL drug mechanism + indication proxy
Approved-linked Open Targets-ready proxy 1 linked drug
Open disease block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Probable arabinosyltransferase A as ChEMBL target CHEMBL1877, mapped to UniProt P9WNL9. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Probable arabinosyltransferase A
SINGLE PROTEIN · Mycobacterium tuberculosis
As of 2026-09-14
ChEMBL target ID
CHEMBL1877
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P9WNL9
Probable arabinosyltransferase A
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Probable arabinosyltransferase A is the right protein anchor across sources, using UniProt P9WNL9 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need to confirm why pulmonary tuberculosis is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelProbable arabinosyltransferase A
UniProt AccessionP9WNL9
Component TypeProtein
Sequence Length1094 aa

Probable arabinosyltransferase A

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Probable arabinosyltransferase A, mapped to UniProt P9WNL9. Sequence length is 1094 aa.

Mapped IDP9WNL9
Review nameProbable arabinosyltransferase A
OrganismMycobacterium tuberculosis
Disease Relevance

Disease Relevance & Evidence Level

Open Targets-ready disease context using the current target-indication evidence contract.

Approved-linked Open Targets-ready proxy

Probable arabinosyltransferase A shows approved-linked disease relevance led by pulmonary tuberculosis. 3 more disease programs remain visible in the same review block.

Approved-linked Approved
pulmonary tuberculosis
1 linked drug · 1 direct · 1 efficacy
Linked drugETHAMBUTOL HYDROCHLORIDE
Approved-linked Approved
tuberculosis
1 linked drug · 1 direct · 1 efficacy
Linked drugETHAMBUTOL HYDROCHLORIDE
Late clinical Phase III
Mycobacterium avium complex disease
1 linked drug · 1 direct · 1 efficacy
Linked drugETHAMBUTOL HYDROCHLORIDE
Clinical signal Phase I
HIV infection
1 linked drug · 1 direct · 1 efficacy
Linked drugETHAMBUTOL HYDROCHLORIDE
Source · ChEMBL drug mechanism + indication proxy
Review Cue

How to read disease relevance

Start review with pulmonary tuberculosis because it currently carries approved-linked support. Linked drugs include ETHAMBUTOL HYDROCHLORIDE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Lead diseasepulmonary tuberculosis
Strongest levelApproved-linked
Block modeOpen Targets-ready proxy
Assay Mix

Activity Type Distribution

IC503.0
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

2
Total Assays
3
Tested Compounds
1
Assay Types
Binding — 2 assays, 3 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 2 3

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine